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Thats the most under rated load for a fast twist 45 yet it has more energy at 100 yards than a 44mag 300gr has at the muzzle. Using just 70grV of BH209 its leaving the muzzle at over 1300fps. 80grV is over 1400fps...Around 1450-1500fps iirc.I dont shoot past 200 yards with my .45 Disc 1:20” but i do shoot 345 and 340 grain lead bullets on bh209. The 330Gould, which i modified to be a flat round nose instead of a hollow-point so it drops at 345grain, is what i would shoot to 300yards. Also, its a hammer on white tails.
350ish-420gr lead is what i want to shoot out of the Ulite barrel i got coming. Easier on powder and the shoulder but still plenty effective. Just compare old 45-90-420 load data. The BH209 load beats the old BPCR load and its closer to a 45-100 type load. That load killed all kinds of big game out to 300 yards.
In a Mountaineer you can easily go upto the 460gr-490gr conicals and upto 80gr of BH209 by volume. That is easily a bison and elk load. It will plow thru a deer like butter.