I’ve personally tested loads up to 115 gr by weight of BH209 in a 22” barrel (designed for high pressure loads). Velocity was still increasing even at that charge weight. So, I think there are a lot of misconceptions out there about the max charge that can physically be burned. Pressure/safety is another question, of course.
Frankly, I couldn’t care less about “wasting” powder. What I am looking for is a combination of precision and velocity in my loads.
The only concern for me with excess powder is any unburned powder granules continuing to impact the base of the bullet after it leaves the muzzle (when it is very susceptible to destabilizing forces) causing greater dispersion. This has been well established in modern firearms.