Welcome to the forum. It is good to have you here.
I know very little about a .45 caliber inline. But if I owned one, I would be shooting one of the following; a Barnes all copper Expander, Nosler HG Partition, Shockwave in as heavy a weight as I could find, and last a Parker Ballistic Extreme if they even make one for the .45 caliber.
As for powder, shoot loose. I would try both Pyrodex RS and Triple Se7en 2f. Start at 80 grains and work up, from there. If you still have accuracy with 110 grains of powder that would be more then enough power to do 150 yard shooting. Put one of them in bullets in the right place, and let it do the work for you.
I have hunted with powerbelts, they are accurate, but I have never shot at an animal with them in the field. So I do not have any field experience with them. Normally I hunt with a patched roundball in a traditional rifle. It seems the only time I see deer is when I have one of them.
But I am going to fool them tomorrow. I have my Renegade with a 1X scope on it, and a Green Mountain Barrel with a 1:28 twist, shooting 120 grains of loose Graf's & Sons 2f black powder and a .430 diameter 300 grain Hornady XTP in a crushed rib sabot. Most my shots will be 50 yards or less, so they will see that old Renegade, figure they are safe and come out. How's that for evil logic..