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If i was shooting the Acurra 45 1-22 LR i would be looking at heavier conicals too. A 350gr will shoot fine but if long range is the goal something over 400gr is a better choice. Dan at BS has a interesting mold. Its a 405 or 415gr HP when cast in his normal alloy. In pure lead or 30-1 it might be 420+. Even that is on the smaller side for a 1-22. You can shoot at least a Bullshop 488 no problem.